Build an Opportunity Solution Tree (OST) to structure product discovery — map a desired outcome to opportunities, solutions, and experiments. Based on Teresa Torres' Continuous Discovery Habits. Use when structuring discovery work, mapping opportunities to solutions, or deciding what to build next.
Generate professional clinical decision support (CDS) documents for pharmaceutical and clinical research settings, including patient cohort analyses (biomarker-stratified with outcomes) and treatment recommendation reports (evidence-based guidelines with decision algorithms). Supports GRADE evidence grading, statistical analysis (hazard ratios, survival curves, waterfall plots), biomarker integration, and regulatory compliance. Outputs publication-ready LaTeX/PDF format optimized for drug development, clinical research, and evidence synthesis.
Integration with protocols.io API for managing scientific protocols. This skill should be used when working with protocols.io to search, create, update, or publish protocols; manage protocol steps and materials; handle discussions and comments; organize workspaces; upload and manage files; or integrate protocols.io functionality into workflows. Applicable for protocol discovery, collaborative protocol development, experiment tracking, lab protocol management, and scientific documentation.
Use when working with code refactoring context restore
Expert patterns for Shopify app development including Remix/React Router apps, embedded apps with App Bridge, webhook handling, GraphQL Admin API, Polaris components, billing, and app extensions. Use when: shopify app, shopify, embedded app, polaris, app bridge.
TypeScript and JavaScript expert with deep knowledge of type-level programming, performance optimization, monorepo management, migration strategies, and modern tooling. Use PROACTIVELY for any TypeScript/JavaScript issues including complex type gymnastics, build performance, debugging, and architectural decisions. If a specialized expert is a better fit, I will recommend switching and stop.
Applies Anthropic's official brand colors and typography to any sort of artifact that may benefit from having Anthropic's look-and-feel. Use it when brand colors or style guidelines, visual formatting, or company design standards apply.
Automate SimilarWeb tasks via Rube MCP (Composio): website traffic, rankings, and digital market intelligence. Always search tools first for current schemas.
Create sales-ready competitive battlecards comparing your product against a specific competitor — positioning, feature comparison, objection handling, and win/loss patterns. Use when preparing sales teams, creating competitive materials, or responding to 'why not competitor X?'
每日阅读工作流 — 基于阅读清单逐篇引导阅读、深度分析、思考记录和素材汇总。适用场景:(1) 开始今天的阅读,(2) 逐篇引导式阅读,(3) 记录阅读思考和观点,(4) 汇总阅读素材用于内容创作,(5) 对文章做快速或深度分析,(6) 建立每日阅读习惯。触发短语:'开始阅读', '今天的阅读', '继续阅读', '阅读工作流', '逐篇阅读', 'start reading', 'reading workflow', 'continue reading', '帮我读', '阅读引导', '边读边想', '阅读笔记', '读完了,下一篇', 'next article', '阅读素材汇总'
This skill should be used for time series machine learning tasks including classification, regression, clustering, forecasting, anomaly detection, segmentation, and similarity search. Use when working with temporal data, sequential patterns, or time-indexed observations requiring specialized algorithms beyond standard ML approaches. Particularly suited for univariate and multivariate time series analysis with scikit-learn compatible APIs.
This skill should be used when working with genomic interval data (BED files) for machine learning tasks. Use for training region embeddings (Region2Vec, BEDspace), single-cell ATAC-seq analysis (scEmbed), building consensus peaks (universes), or any ML-based analysis of genomic regions. Applies to BED file collections, scATAC-seq data, chromatin accessibility datasets, and region-based genomic feature learning.
Neuropixels neural recording analysis. Load SpikeGLX/OpenEphys data, preprocess, motion correction, Kilosort4 spike sorting, quality metrics, Allen/IBL curation, AI-assisted visual analysis, for Neuropixels 1.0/2.0 extracellular electrophysiology. Use when working with neural recordings, spike sorting, extracellular electrophysiology, or when the user mentions Neuropixels, SpikeGLX, Open Ephys, Kilosort, quality metrics, or unit curation.
Full-featured computational pathology toolkit. Use for advanced WSI analysis including multiplexed immunofluorescence (CODEX, Vectra), nucleus segmentation, tissue graph construction, and ML model training on pathology data. Supports 160+ slide formats. For simple tile extraction from H&E slides, histolab may be simpler.
Every product will be AI-powered. The question is whether you'll build it right or ship a demo that falls apart in production. This skill covers LLM integration patterns, RAG architecture, prompt engineering that scales, AI UX that users trust, and cost optimization that doesn't bankrupt you. Use when: keywords, file_patterns, code_patterns.
Select and optimize embedding models for semantic search and RAG applications. Use when choosing embedding models, implementing chunking strategies, or optimizing embedding quality for specific domains.
[Extended thinking: This workflow implements a sophisticated debugging and resolution pipeline that leverages AI-assisted debugging tools and observability platforms to systematically diagnose and res
Develop native iOS applications with Swift/SwiftUI. Masters iOS 18, SwiftUI, UIKit integration, Core Data, networking, and App Store optimization. Use PROACTIVELY for iOS-specific features, App Store optimization, or native iOS development.